Menopause 101

On this page:
Understanding the Different Types of Menopause
Natural (Spontaneous) Menopause
Early Menopause
Premature Menopause
Primary (or Premature) Ovarian Insufficiency (POI)
POI vs Premature or Induced Menopause – Why It’s So Confusing
Induced Menopause (or Medically-Induced Menopause)
Surgical Menopause (or Surgically-Induced Menopause)
Chemical Menopause (or Chemically-Induced Menopause)
Timeline of Menopause
References

Primary (or Premature) Ovarian Insufficiency (POI)

Primary (or Premature) Ovarian Insufficiency (POI) – previously known as Primary Ovarian Failure (POF) – is a condition where the ovaries lose normal function before age 40. It affects about 1% of women under 40 and 0.1% of women under 30. POI leads to irregular or absent periods, infertility, and reduced hormone production. It’s a clinical diagnosis made when a woman under 40 has:

  • Signs of reduced or absent ovarian function
  • Irregular or absent periods (amenorrhea) for at least 4 months
  • Elevated follicle-stimulating hormone (FSH) levels on two separate tests

POI can have a range of causes, including genetic and autoimmune conditions, or medical treatments. Hormone replacement therapy (HRT) is commonly recommended to manage symptoms and help protect bone and cardiovascular health.

POI vs Premature or Induced Menopause – Why It’s So Confusing

POI is a medical diagnosis used to describe reduced or absent ovarian function before age 40. However, in clinical literature and research, the term is often used as an umbrella that includes not only spontaneous POI (from autoimmune, genetic, or unknown causes), but also menopause caused by medical treatments or surgery.

This can be frustrating – particularly for those who’ve had a bilateral oophorectomy (surgical removal of both ovaries) – as they no longer have ovaries at all. In such cases, the idea of “insufficiency” isn’t just technically inaccurate; it can feel dismissive of the reality that their ovarian function is not diminished – it is entirely absent and irreversible.

For more information on POI, visit Early Menopause New Zealand.